At the beginning, there is no difference, but memory increases over time, it is better to have mutable JavaScript objects. They are also very fast compared to ClojureScript ones. For performance-sensitive apps, it is crucial not to trigger garbage collection very often. Here is a nice video where the author of Lightable talks about making ClojureScript games: https://youtu.be/V1Eu9vZaDYw?t=268

Ah, sweet 😊