I think the issue is System Integrity Protection https://github.com/oracle/node-oracledb/issues/231

Okay, new problem, with the JCudaDriver returning CUDA_ERROR_NOT_INITIALIZED. I've made sure /Developer/NVIDIA/CUDA-8.0/lib/ libraries are available and /Developer/NVIDIA/CUDA-8.0/bin/ is on my path. Is there another requirement?

@aria42 You haven't given any details about which library are you trying to use and what exactly did you try. There is an example hello world in the neanderthal github source, so you should try to run this first. As for the CUDA stuff, I've used that on linux, and there everything works out of the box once you install CUDA toolbox. I'm not sure if there is another requirement on OSX. In any case, make sure you've read the getting started documentation first.