@kasuko: Personally, I use Datascript and not FRP and I'm super happy with it. Though these guys are doing exactly what you're describing (without Reagi but different FRP): https://github.com/uxbox/uxbox/tree/master/src/uxbox

Mostly uses stuff from funcool, like wrapping RxJS: https://github.com/funcool/beicon (also see the project.clj)